Improved Molecular Diagnosis of McCune–Albright Syndrome and Bone Fibrous Dysplasia by Digital PCR

Fibrous Dysplasia of Bone

Fibrous dysplasia is a disease which may be manifested in a single bone as tumefaction or a solitary cyst (monostotic type), in a region involving contiguous bones, or in a diffuse manner (polyostotic type), the latter possibly in association with endocrine and developmental disturbances. The condition is of interest to the neurological surgeon when the cranial or cranio-facial structures are i...

Molecular diagnosis of Mycoplasma spp. Arthritis by PCR

Background: Arthritis is one of the most common inflammatory diseases worldwide. It is characterized by symptoms such as systemic inflammation and autoantibody production. The molecular mechanisms in pathogenesis of arthritis are not fully understood. Studies show that many microorganisms, including Mycoplasmas, play a role in arthritis. The PCR method is a fast and accurate molecular method fo...

[Polyostotic fibrous dysplasia: Albright's syndrome].

[3 cases of fibrous dysplasia of bone].

Clinical history and examination A TWENTY-FOUR year old soldier was seen on 4 March 1969 with a two month history of cramp-like pains in the right thigh and front of right leg. Pain was intermittent, aggravated by standing for more than a half hour, or walking more than a half mile. Five years ago he had received a direct blow to the right tibia in a traffic accident and since then he had notic...

Craniofacial Fibrous Dysplasia

Fibrous dysplasia (FD) is an osseous growth dis-order, producing immature bone and characte-rized by the replacement of normal bone with fibro-osseous connective tissue. It is a bone dys-plasia that has the potential to cause significant cosmetic and functional disturbances, particularly in the craniofacial skeleton. Cra-niofacial fibrous dysplasia is one of the three types of polyostotic fibro...